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With a pronounced allergic restructuring, brucellin is used, but most often a special (killed) therapeutic vaccine. The live vaccine is prescribed only for Essay Services. Various methods of vaccine administration have been proposed: intravenous, intramuscular, subcutaneous and intradermal.
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It must be remembered that an inaccurate dosage of the vaccine can lead to an exacerbation of the disease (with an overdose) or to the absence of a pronounced effect (with an insufficient dose). In this regard, the choice of the method of administration and the calculation of the individual dose plays an important role.
The greatest distribution in the treatment of Essay Writing Service brucellosis received subcutaneous and intradermal administration of the vaccine. Subcutaneously, the vaccine is prescribed for worsening of the course of brucellosis and with a pronounced process. An important principle of vaccine therapy is the individual selection of the dose of the drug.
To some extent, the severity of the reaction is judged by the intensity of the Burne test. Subcutaneous administration often begins with 10-50 million microbial cells. If there are no local and general reactions, then the vaccine in an increased dose is administered the very next day.
For treatment, a dose is selected that causes a moderate reaction. The next injection of the vaccine is done only after the reaction to the previous injection of the vaccine has disappeared. A single dose at the end of the course is adjusted to 1-5 billion microbial cells.
Intradermal vaccine therapy is more gentle. This method is used in the stage of paper writing, as well as during the transition of brucellosis into a latent form. According to the severity of the skin reaction, a working dilution of the vaccine is selected (it should cause a local reaction in the form of reddening of the skin with a diameter of 5 to 10 mm). The vaccine is injected intradermally into the palmar surface of the forearm on the first day, 0.1 ml in 3 places, then 1 injection is added every day and brought up to 10 injections on the 8th day.
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If the response to the vaccine decreases, to take a more concentrated dilution. It should be borne in mind that even with the complete disappearance of all clinical manifestations, 20-30% may experience an exacerbation of the disease in the future. The prognosis for life with brucellosis is favorable.
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Compliance with preventive measures in the care of animals. Vaccination and revaccination with a live anti-brucellosis vaccine of persons at risk for brucellosis. Important! All materials are for reference only and are in no way an alternative to in-person consultation with a specialist. This site uses cookies to identify site visitors: Google analytics, Yandex metrica, Google Adsense. If this is not acceptable to you, please visit this page anonymously.
The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!
The causative agents of brucellosis are bacteria from the genus Brucella (Brucella), the main habitat of which are domestic and wild animals. In animals, these microorganisms do not cause an obvious clinical picture of the disease, but can lead to mass abortions and other pathologies.
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Although Brucella are considered intracellular parasites (developing inside the cells of the host organism), they can remain outside the cells for a long time. They are also quite stable in the external environment, but can be destroyed by various chemical and physical factors.
Prevention of the disease is based on the fight against brucellosis in farm animals.
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Dangerous to humans are: B. melitensis - the main hosts are sheep, goats and other small cattle. B. abortus - develops mainly in cattle. B. suis is typical for pigs and wild animals (hares, deer). B. canis - dogs are the main reservoir. All types of Brucella are characterized by a high invasive ability, that is, they can easily enter the human body through mucous membranes or damaged skin.
Brucella can survive: In water - up to 2 months. In raw meat - up to 3 months. In animal hair - up to 4 months. At a temperature of 60 degrees - up to 30 minutes. When boiled, these microorganisms die almost instantly, as well as when exposed to various disinfectant solutions (0.2 - 1% bleach solution, chloramine, and so on).
From animal to human, brucellosis can be transmitted: Fecal-oral (food) route. This is the main route of infection, in which bacteria enter the human body through the mucous membranes of the digestive system (when a person comes into contact with the urine or feces of infected animals and personal hygiene is not followed).
